• Pediatr Crit Care Me · Oct 2018

    Cognitive and Behavioral Consequences of Pediatric Delirium: A Pilot Study.

    • Jochen Meyburg, Markus Ries, Matthias Zielonka, Karin Koch, Anja Sander, Rebecca von Haken, and Gitta Reuner.
    • Pediatric Intensive Care, Department of General Pediatrics, Centre for Pediatric and Adolescent Medicine, University Hospital Heidelberg, Heidelberg, Germany.
    • Pediatr Crit Care Me. 2018 Oct 1; 19 (10): e531-e537.

    ObjectivesTo investigate the long-term impact of postoperative delirium in children.DesignSingle-center point prevalence study.SettingTwenty-two bed PICU.PatientsForty-seven patients 1-16 years old.InterventionsStandardized neuropsychologic follow-up investigation after a mean time of 17.7 ± 2.9 months after PICU discharge.Measurements And Main ResultsPediatric delirium did not have significant long-term impact on global cognition, executive functions, or behavior. Severity of delirium did not influence the outcome. Different predictors were identified for later cognitive functioning, executive functions, and behavioral problems. Younger age was confirmed to be a relevant risk factor for delirium as well as for the cognitive and behavioral outcome.ConclusionsContrary to the findings in adults, there was no clear association between pediatric delirium and long-term cognition or behavior in this cohort. However, this is a first pilot study with several limitations that should promote more comprehensive prospective trials.

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