• Yun Ji, Baoli Cheng, Zhipeng Xu, Hui Ye, Weina Lu, Xiaoqian Luo, Shuiqiao Fu, and Xiangming Fang.
• Surgical Intensive Care Unit, Department of General Surgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, 88 Jiefang Road, Hangzhou, China, 310009; Department of Anesthesiology, The First Affiliated Hospital, School of Medicine, Zhejiang University, 79 QingChun Road, Hangzhou, China, 310003.
• J Crit Care. 2018 Aug 1; 46: 50-54.

PurposeThis study aimed to investigate the association between sarcopenic obesity and 30-day mortality in critically ill patients with intra-abdominal sepsis.Material And MethodsWe analyzed 236 surgical ICU patients with sepsis due to intra-abdominal infection who underwent urgent surgical intervention. Sarcopenia, visceral obesity and sarcopenic obesity were analyzed by computed tomography scans using the third lumbar vertebrae skeletal muscle index and visceral adipose tissue area, using previously reported cutoff values.ResultsThe cohort was divided into 4 groups: 52 were diagnosed with sarcopenic obesity, 62 with sarcopenia only, 58 with visceral obesity only, and 64 with no sarcopenia or visceral obesity. 57 (24.2%) patients died within 30days. The frequency of 30-day mortality differed significantly among the groups. Multivariate analysis showed that only sarcopenic obesity was associated with increased risk for 30-day mortality. Sarcopenic patients were older than non-sarcopenic patients. To address this limitation, subgroup analyses stratified by age showed that the risk of 30-day mortality increased significantly in sarcopenic patients, both in patients with age≤70years and in those with age >70years.ConclusionSarcopenic obesity is an independent risk factor for 30-day mortality in critically ill patients with intra-abdominal sepsis.Copyright © 2018 Elsevier Inc. All rights reserved.

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