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- Kaiser G Lim, Timothy I Morgenthaler, and David A Katzka.
- Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN; Division of Allergic Diseases, Mayo Clinic, Rochester, MN. Electronic address: lim.kaiser@mayo.edu.
- Chest. 2018 Oct 1; 154 (4): 963-971.
AbstractNocturnal gastroesophageal reflux has been associated with poor sleep quality. Normal physiological adaptations of the aerodigestive system to sleep prolong and intensify nocturnal reflux events. This occurrence leads to sleep disruption, as well as to esophageal, laryngeal, and laryngopharyngeal reflux. Controversy exists on whether OSA and nocturnal reflux are causally linked or merely associated because of shared risk factors. Advances in diagnostic technology have provided new insights into gastroesophageal reflux and the mechanisms of nocturnal reflux during sleep. This update reviews new data on causal links between sleep and gastroesophageal reflux disease.Copyright © 2018 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.
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