• Critical care clinics · Jul 2018

    Review

    Complications of Durable Left Ventricular Assist Device Therapy.

    • Sitaramesh Emani.
    • Advanced Heart Failure and Cardiac Transplant, Division of Cardiovascular Medicine, The Ohio State University Wexner Medical Center, 473 West 12th Avenue, Suite 200 DHLRI, Columbus, OH 43221, USA. Electronic address: Sitaramesh.emani@osumc.edu.
    • Crit Care Clin. 2018 Jul 1; 34 (3): 465-477.

    AbstractHeart failure patients on durable left ventricular assist device support experience improved survival, quality of life, and exercise capacity. The complication rate, however, remains unacceptably high, although it has declined with improvements in pump design, better patient selection, and greater understanding of the pump physiology and flow dynamics. Most complications are categorized as those related to the pump-patient interface or those related to patient physiology. It is hoped that further engineering progress, and better patient selection through risk stratification, will allow for left ventricular assist device to be totally biocompatible and perform effectively, without affecting biology and homeostasis of the different organ systems.Copyright © 2018 Elsevier Inc. All rights reserved.

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