• Munehiro Iiya, Masato Shimizu, Kohei Takahashi, Hiroyuki Fujii, Makoto Suzuki, Noriyoshi Yamawake, and Mitsuhiro Nishizaki.
• Department of Cardiology, Yokohama Minami Kyosai Hospital, 1-21-1 Mutsuura-higashi, Kanazawa-ku, Yokohama 236-0037, Japan. Electronic address: iiya_munehiro@yahoo.co.jp.
• J Crit Care. 2018 Oct 1; 47: 269-273.

PurposeTo predict neurological outcome following out-of-hospital cardiac arrest (OHCA) using a combination of hemoglobin (Hb) and low-flow duration (LFD).Materials And MethodsWe retrospectively examined 131 patients (75 ± 13 years, 64 men) with return of spontaneous circulation (ROSC) following non-traumatic OHCA. The LFD was the duration from the start of cardiopulmonary resuscitation to ROSC. To obtain the Hb/LFD value, we divided the Hb level by the LFD. Multivariate logistic regression analyses were performed to predict full neurological recovery (FNR), defined as Cerebral Performance Category scale scores of 1 or 2 at discharge.ResultsNineteen patients (15%) achieved FNR. Patients with FNR had high Hb levels (14.9 ± 2.1 vs. 11.3 ± 2.7 g/dl, p = 0.001) and short LFDs (10 [5, 18] vs. 35 [28, 43] min, p = 0.001). Multivariate analyses identified the initial ventricular fibrillation rhythm and Hb/LFD as significant predictors for FNR (odds ratio: 24.9, 3.58; p = 0.001, 0.02, respectively). Receiver operating characteristic (ROC) curve analyses indicated that a high Hb/LFD predicted FNR (cut-off value: 0.50, sensitivity: 94.7%, specificity: 84.5%, area under the curve: 0.933).ConclusionsPatients with FNR following OHCA had high Hb levels and short LFDs; the Hb/LFD value significantly predicted FNR.Copyright © 2018 Elsevier Inc. All rights reserved.

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