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- Juan P Cata.
- Department of Anesthesiology and Perioperative Medicine, The University of Texas -MD Anderson Cancer Center; Anesthesia and Surgical Oncology Research Group, Houston, Texas, USA.
- Curr Opin Anaesthesiol. 2018 Oct 1; 31 (5): 593-600.
Purpose Of ReviewTo summarize the current evidence on the impact of regional anesthesia or analgesia on cancer recurrence.Recent FindingsPreclinical investigations suggest that regional anesthesia could have a positive impact on reducing cancer growth and progression. Regional anesthesia is also associated with better immunological and stress-related outcomes in patients undergoing major oncological surgery. Most recent retrospective studies do not show any benefit of regional anesthesia or analgesia on cancer recurrence or recurrence-free survival.SummaryThe available clinical evidence does not support the use of any anesthesia technique to improve the cancer-related survival after major oncological surgery. The results from four randomized controlled trials will shed light on this critical topic in perioperative medicine.
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