• Donata Ringaitiene, Lina Puodziukaite, Vaidas Vicka, Dalia Gineityte, Mindaugas Serpytis, and Jurate Sipylaite.
• Department of Anesthesiology and Intensive Care, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, Vilnius, Lithuania. Electronic address: dringaitiene@yahoo.com.
• J. Cardiothorac. Vasc. Anesth. 2019 Apr 1; 33 (4): 969-975.

ObjectiveTo determine whether bioelectrical impedance-derived phase angle (PA) can be a predictor of red blood cell (RBC) transfusion in patients undergoing cardiac surgery.DesignAn observational retrospective study of prospectively collected data.SettingSingle center, tertiary referral university hospital.ParticipantsThe study sample comprised 642 adult patients undergoing elective cardiac surgery.InterventionsPatient demographic and clinical variables were collected. The body composition of the patients was evaluated by bioelectrical impedance analysis (BIA) the day prior to surgery. The rates of postoperative RBC transfusion were recorded.Measurements And Main ResultsAmong the 642 patients (67.8% men, median age of 66 [range 59-73]) included in the present study, 210 (32.7%) received at least 1 RBC unit postoperatively. Hypertension, preoperative stroke, renal failure, preoperative hemoglobin and hematocrit values, BIA-derived PA, aortic crossclamp time, and cardiopulmonary bypass (CPB) time were associated with the risk of RBC transfusion in the univariate analysis, and were included in the final multivariate regression model. Preoperative stroke (odds ratio [OR] 0.394; 95% confidence interval [CI]: 0.183-0.848; p = 0.017), preoperative hemoglobin values (OR 0.943; 95% CI: 0.928-0.960; p < 0.001), PA <15th percentile (OR 2.326; 95% CI: 1.351-4.000; p = 0.002), and CPB time (OR 1.013; 95% CI: 1.008-1.018; p < 0.001) were identified as independent predictors of RBC transfusion.ConclusionSeveral factors were identified to be associated significantly with postoperative RBC transfusion in patients undergoing cardiac surgery. Among the conventional predictors, the value of the BIA-derived PA was indicated as a potent prognostic tool.Copyright © 2018 Elsevier Inc. All rights reserved.

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