• J. Cardiothorac. Vasc. Anesth. · Mar 2019

    Observational Study

    Preoperative Right Ventricular Dysfunction Indicates High Vasoactive Support Needed After Cardiac Surgery.

    • Pei-Chi Ting, Victor C-C Wu, Chia-Chih Liao, An-Hsun Chou, Feng-Chun Tsai, Pyng-Jing Lin, Chun-Yu Chen, and Shao-Wei Chen.
    • Department of Anesthesiology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
    • J. Cardiothorac. Vasc. Anesth. 2019 Mar 1; 33 (3): 686-693.

    ObjectiveThe aim of this study was to explore the relationship between preoperative right ventricular (RV) function and high vasoactive-inotropic score (VIS) after cardiac surgery.DesignProspective observational study.SettingA single medical center setting.ParticipantsOne hundred three patients undergoing elective cardiac surgery.InterventionsNone.Measurements And Main ResultsConsecutive patients referred for cardiac surgery were enrolled prospectively. Comprehensive transesophageal echocardiography was performed before sternal incision. Specific RV indices, encompassing RV fractional area change, tricuspid annular plane systolic excursion, and RV global longitudinal strain (RVGLS), were measured offline. High VIS was defined as a maximum VIS of ≥20 in 24 hours postoperatively. Postoperative adverse events were recorded. One hundred three patients (mean age 61.2 ± 11.0, 72 men) were included in this study, where 17 patients (16.5%) achieved high VIS with a mean maximum VIS of 39 in 24 hours postoperatively. Patients with high VIS encountered increased occurrence of extracorporeal membrane oxygenation placement, acute kidney injury, and mortality. Risk factors for high VIS included operation type, cardiopulmonary bypass duration, left atrium size, and pre-incisional RV indices. After adjustment for age, left ventricular ejection fraction, and the covariates, only RVGLS (odds ratio 1.19, p = 0.011) showed an independent association with high VIS. The optimal cutoff of RVGLS was -16.7% (sensitivity of 88.2%, specificity of 75.6%).ConclusionPreoperative RV dysfunction is an independent risk factor for postoperative high VIS. Pre-incisional RVGLS is a reliable tool to predict high VIS after cardiac surgery. Patients with high VIS had increased adverse events postoperatively.Copyright © 2018 Elsevier Inc. All rights reserved.

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