• Spine · Apr 2019

    Randomized Controlled Trial Multicenter Study

    Patients cannot Reliably Distinguish the Iliac Crest Bone Graft Donor Site From the Contralateral Side after Lumbar Spine Fusion: A Patient-Blinded Randomized Controlled Trial.

    • A Mechteld Lehr, F Cumhur Oner, Eric A Hoebink, Diederik H R Kempen, van Susante Job L C JLC Department of Orthopaedic Surgery, Rijnstate Hospital, Arnhem, The Netherlands., René M Castelein, and Moyo C Kruyt.
    • Department of Orthopaedic Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.
    • Spine. 2019 Apr 15; 44 (8): 527-533.

    Study DesignA multicenter, randomized, intrapatient controlled trial.ObjectiveThis study investigated whether lumbar fusion patients blinded to the harvest site (A) can identify the iliac crest used for bone harvesting and (B) whether this iliac crest is more painful than the contralateral side.Summary Of Background DataSpinal fusion with iliac crest autograft is a frequently performed surgical procedure. A widely reported disadvantage of the harvesting procedure is potential donor site morbidity. This has driven the development of many bone graft substitutes. However, more recently the incidence and severity of donor site pain is debated, especially in lumbar fusion surgery.MethodsNinety-two nontraumatic adult patients underwent a posterolateral (thoraco)lumbar fusion. Iliac crest bone graft was harvested unilaterally through the primary midline incision. At 6 weeks, 3 months, 6 months, and 1 year follow-up, patients were asked to identify the donor site and to rate pain in their back, left iliac crest and right iliac crest on a Visual Analogue Scale (VAS).ResultsNinety patients, 44 males and 46 females with a mean age of 54 years, were analyzed. The left/right distribution of the iliac crest donor site was 50/50 and 89% of the patients underwent a lumbar fusion below L3. Only 24% patients identified the harvest site correctly. Moreover, the VAS pain scores for the donor site and contralateral iliac crest did not differ and were at each timepoint lower than the scores for back pain.ConclusionThis study showed that, during the first year after lumbar fusion surgery via a single midline incision approach, patients could not reliably identify the iliac crest used for bone graft harvesting and this iliac crest was not more painful than the untouched contralateral iliac crest. Therefore, donor site pain should not be the main reason to use bone graft alternatives for lumbar spinal fusion.Level Of Evidence2.

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