• Eckhard Mauermann, Wilhelm Ruppen, and Oliver Bandschapp.
• University Hospital Basel, Department for Anesthesia, Surgical Intensive Care, Prehospital Emergency Medicine and Pain Therapy, Spitalstrasse 21, 4031 Basel, Switzerland; University Hospital Ghent, Department of Anesthesiology and Perioperative Medicine, Building K12-C 2nd Floor, De Pintelaan 185, B-9000, Ghent, Belgium.
• Best Pract Res Clin Anaesthesiol. 2017 Dec 1; 31 (4): 533-545.

AbstractWith increasing awareness of both short- and long-term problems associated with liberal perioperative opioid administration, the need for routinely and clinically feasible alternatives is greater than ever. Opioid-free anesthesia-previously reserved for bariatric surgery-is receiving increasing attention in mainstream anesthesia. In this review, we present the truly multimodal concept of opioid-free anesthesia, which circumvents a number of opioid-related problems. For a concrete clinical perspective, we present in depth our opioid-free protocol for bariatric surgery. However, clinicians must be aware of potential problems related to opioid-free anesthesia.Copyright © 2017 Elsevier Ltd. All rights reserved.

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