• Matthew A Kirkman, Jessica C Pickles, Amy R Fairchild, Aimee Avery, Torsten Pietsch, Thomas S Jacques, and Kristian Aquilina.
• Department of Neurosurgery, Great Ormond Street Hospital, London, United Kingdom; Victor Horsley Department of Neurosurgery, The National Hospital for Neurology and Neurosurgery, Queen Square, London, United Kingdom.
• World Neurosurg. 2018 Aug 1; 116: 279-284.

BackgroundAdvances in molecular profiling have facilitated the emergence of newly defined entities of central nervous system (CNS) tumor, including CNS high-grade neuroepithelial tumor with BCOR alteration (CNS HGNET-BCOR). Relatively little is known about the clinical behavior of these newly characterized tumors.Case DescriptionWe describe a pediatric male patient with CNS HGNET-BCOR, who developed seeding of the tumor into the site of the surgical wound within months of surgery and who underwent resection of a residual posterior fossa tumor.ConclusionsThis case emphasizes 3 important points. First, CNS HGNET-BCOR can be aggressive tumors that necessitate close clinical and radiologic surveillance. Second, surveillance imaging in such cases should incorporate the surgical incision site into the field of view, and this should be closely scrutinized to ensure the timely detection of wound site seeding. Third, wound site seeding may still occur despite the use of meticulous surgical techniques.Crown Copyright © 2018. Published by Elsevier Inc. All rights reserved.

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