• Emerg. Med. Clin. North Am. · Nov 2018

    Review

    Emergency Department Approach to the Patient with Suspected Central Nervous System Infection.

    • Rupal Jain and Chang Wan-Tsu W WW Department of Emergency Medicine, University of Maryland School of Medicine, 110 South Paca Street, 6th Floor, Suite 200, Baltimore, MD 21201, USA. Ele.
    • Department of Emergency Medicine, University of Maryland Medical Center, University of Maryland School of Medicine, 110 South Paca Street, 6th Floor, Suite 200, Baltimore, MD 21201, USA.
    • Emerg. Med. Clin. North Am. 2018 Nov 1; 36 (4): 711-722.

    AbstractCentral nervous system (CNS) infections require early recognition and aggressive management to improve patient survival and prevent long-term neurologic sequelae. Although early detection and treatment are important in many infectious syndromes, CNS infections pose unique diagnostic and therapeutic challenges. The nonspecific signs and symptoms at presentation, lack of characteristic infectious changes in laboratory and imaging diagnostics, and closed anatomic and immunologically sequestered space each present challenges to the emergency physician. This article proposes an approach to the clinical evaluation of patients with suspected CNS infection and highlights methods of diagnosis, treatment, and complications associated with CNS infections.Copyright © 2018 Elsevier Inc. All rights reserved.

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