Clot Pathophysiology: Why Is It Clinically Important?

Neuroimaging Clin. N. Am. · Nov 2018

Review Case Reports

Clot Pathophysiology: Why Is It Clinically Important?

Cerebral ischemic stroke treatment may change significantly now that clots are actually physically removed from the patient using thrombectomy. This allows for an analysis of the content of the clots as well as the correlation of the imaging findings and the clot behavior and morphology. This article illustrates how the interaction of different clots varies in the clinical setting and how analysis of clot composition, as well as the search for new pharmacologic targets, can lead to a better understanding of the pathophysiology and therapy resistance, in turn providing possibilities for a better approach in the treatment.

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- Patrick A Brouwer, Waleed Brinjikji, and Simon F De Meyer.
- Neuroradiology Department, Neurointervention Section, Karolinska University Hospital, Eugeniavägen 3, Stockholm, 171 64 Solna, Sweden. Electronic address: patrickbrouwermd@gmail.com.
- Neuroimaging Clin. N. Am. 2018 Nov 1; 28 (4): 611623611-623.
AbstractCerebral ischemic stroke treatment may change significantly now that clots are actually physically removed from the patient using thrombectomy. This allows for an analysis of the content of the clots as well as the correlation of the imaging findings and the clot behavior and morphology. This article illustrates how the interaction of different clots varies in the clinical setting and how analysis of clot composition, as well as the search for new pharmacologic targets, can lead to a better understanding of the pathophysiology and therapy resistance, in turn providing possibilities for a better approach in the treatment.Copyright © 2018 Elsevier Inc. All rights reserved.

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Clot Pathophysiology: Why Is It Clinically Important?

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