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- G Pari and H M Schipper.
- Department of Neurology, Jewish General Hospital, McGill University, Montreal, Quebec, Canada.
BackgroundMajor neurological complications of sickle cell disease include cerebral infarction and intracranial hemorrhages.MethodsWe describe the case of a 25-year-old man with sickle cell disease who developed a severe headache of acute onset, located at the vertex. There was associated pitting edema of the scalp.ResultsTechnetium and gallium bone imaging showed focal decreased uptake of the tracers, consistent with a recent fronto-parietal skull infarction. Management included intravenous hydration and analgesic medication.ConclusionsIn addition to the more common intracranail vaso-occlusive complications, skull infarction should be considered as a cause of newonset headache in patients with sickle cell disease, especially if scalp edema is present.
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