• Curr Pain Headache Rep · Jul 2018

    Review

    Emerging Treatments in Episodic Migraine.

    • Kate W Grimsrud and Rashmi B Halker Singh.
    • Department of Neurology, Mayo Clinic Arizona, Scottsdale, AZ, USA. grimsrud.kate@mayo.edu.
    • Curr Pain Headache Rep. 2018 Jul 16; 22 (9): 61.

    Purpose Of ReviewThe purpose of this review is to evaluate and describe recent and emerging treatment options for episodic migraine.Recent FindingsRecent advances have been made in better understanding the pathophysiology of migraine, which has led to further investigation of potential new pharmacologic and non-pharmacologic treatment options. A number of new medications are emerging for the acute and preventive treatment of migraine, including CGRP monoclonal antibodies, CGRP receptor antagonists, serotonin 5-HT1F agonists, and PACAP receptor monoclonal antibodies. Additionally, newer studies on existing non-invasive neuromodulation devices including transcranial magnetic stimulation, supraorbital transcutaneous nerve stimulation, and transcutaneous vagus nerve stimulation have recently received FDA approval for use in migraine. Neuromodulation devices including percutaneous mastoid electrical stimulation, non-painful remote electrical stimulation, and caloric vestibular stimulation are undergoing further investigation and have shown promising results thus far. These new developments are expected to contribute to better treatment and decreased disability in migraine.

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