• En-Pei Lee, Shao-Hsuan Hsia, Chung-Chi Huang, Kuo-Chin Kao, Oi-Wa Chan, Chia-Ying Lin, Ya-Ting Su, I-Meng Hu, Jainn-Jim Lin, and Han-Ping Wu.
• Division of Pediatric Critical Care Medicine, Pediatric Sepsis Study Group, Department of Pediatrics, Chang Gung Memorial Hospital at Linko, Kweishan, Taoyuan, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan.
• J Crit Care. 2019 Feb 1; 49: 45-49.

PurposeTo compare systemic vascular resistance index (SVRI) as measured by invasive transpulmonary indicator dilution (TPID) and non-invasive Doppler-derived resistive index in septic patients.MethodsWe measured the snuffbox resistive index (SBRI) in both hands of septic patients who received hemodynamic monitoring by TPID prospectively.ResultsThirty-six patients with septic shock were enrolled (median acute physiology and chronic health evaluation II score: 23; median age: 64 years). Four SBRI values were measured in each patient, for a total of 96 patient days and 951 ultrasound measurements. The correlation coefficients between SVRI and the four SBRI values were all higher than 0.87 (p < .001). A higher SVRI was associated with sharp waveforms and reversed diastolic flow. A resistive index (RI) of 0.97 was the lower limit of normal SVRI (1700 dyn*s*cm-5*m2), and an RI of 1.1 was the upper limit of normal SVRI (2400 dyn*s*cm-5*m2).ConclusionsUsing ultrasound to measure RI is a noninvasive, inexpensive, reliable method to evaluate peripheral vascular resistance in septic patients, and it is highly correlated with SVRI. In addition, SBRI can be used to evaluate peripheral circulatory disturbances in septic patients.Copyright © 2018 Elsevier Inc. All rights reserved.

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