• Resuscitation · Feb 2019

    Multicenter Study

    Detailed analysis of health-related quality of life after out-of-hospital cardiac arrest.

    • Mattias Bohm, Gisela Lilja, Hafrún Finnbogadóttir, Tobias Cronberg, Johan Undén, Hans Friberg, Jesper Kjærgaard, Niklas Nielsen, Matt P Wise, and Eva Åkerman.
    • Department of Intensive and Perioperative Care, Skåne University Hospital, Malmö, Sweden. Electronic address: mattias.bohm@skane.se.
    • Resuscitation. 2019 Feb 1; 135: 197-204.

    AimTo describe the detailed health-related quality of life (HRQoL) in survivors from the TTM-trial and to investigate potential differences related to sex and age.MethodsThis is a cross-sectional study originating from a large prospective international, multicentre trial, including 442 respondents who answered the Short Form-36 item Questionnaire Health Survey version 2® (SF-36v2®) at a structured follow-up 6 months after out-of-hospital cardiac arrest (OHCA). Statistical analysis between independent groups were performed with Mann-Whitney U or Chi-square. Age was analysed primarily as a dichotomised variable.ResultsAlthough overall physical and mental health were within the normal range, a substantial proportion of respondents had impaired function at domain-specific levels, particularly in Role-Physical (50%) and Role-Emotional (35%). Females scored significantly lower than males in; Physical Functioning (41.7 vs. 47.9, p < 0.001), Role-Physical (40.4 vs. 44.3, p = 0.02), General Health (47.0 vs. 50.5, p = 0.02), Vitality (47.2 vs. 52.7, p < 0.001), and Role-Emotional (41.5 vs. 46.2, p = 0.009). Those ≤65 years scored significantly better in Physical Functioning (47.9 vs. 44.1 p < 0.001), while those >65 years scored significantly better in Vitality (50.8 vs. 53.7, p = 0.006) and Mental Health (50.3 vs. 52.6, p = 0.04).ConclusionsMany OHCA survivors demonstrated impaired function in HRQoL at a domain level, despite most patients reporting an acceptable general HRQoL. Females reported worse HRQoL than males. Older age was associated with a worse Physical Functioning but better Vitality and Mental Health. Role-Physical and Role-Emotional aspects of health were especially affected, even when effects of age and sex where accounted for.Copyright © 2018 Elsevier B.V. All rights reserved.

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