• J Pain · Jun 2018

    Multicenter Study

    Within-Person Pain Variability and Mental Health in Older Adults With Osteoarthritis: An Analysis Across 6 European Cohorts.

    • Elisa J de Koning, Erik J Timmermans, Natasja M van Schoor, Brendon Stubbs, Tessa N van den Kommer, Elaine M Dennison, Federica Limongi, Maria Victoria Castell, Mark H Edwards, Rocio Queipo, Cyrus Cooper, Paola Siviero, Suzan van der Pas, Nancy L Pedersen, Mercedes Sánchez-Martínez, DeegDorly J HDJHDepartment of Epidemiology and Biostatistics / Amsterdam Public Health Research Institute, Vrije Universiteit Medical Center, Amsterdam, The Netherlands., Michael D Denkinger, and EPOSA Group.
    • Department of Epidemiology and Biostatistics / Amsterdam Public Health Research Institute, Vrije Universiteit Medical Center, Amsterdam, The Netherlands. Electronic address: ej.dekoning@vumc.nl.
    • J Pain. 2018 Jun 1; 19 (6): 690-698.

    AbstractPain is a key symptom of osteoarthritis (OA) and has been linked to poor mental health. Pain fluctuates over time within individuals, but a paucity of studies have considered day-to-day fluctuations of joint pain in relation to affective symptoms in older persons with OA. This study investigated the relationship of pain severity as well as within-person pain variability with anxiety and depression symptoms in 832 older adults with OA who participated in the European Project on OSteoArthritis (EPOSA): a 6-country cohort study. Affective symptoms were examined with the Hospital Anxiety and Depression Scale, pain severity was assessed with the Western Ontario and McMaster Universities OA Index and the Australian/Canadian Hand Osteoarthritis Index, and intraindividual pain variability was measured using pain calendars assessed at baseline, 6, and 12 to 18 months. Age-stratified multiple linear regression analyses adjusted for relevant confounders showed that more pain was associated with more affective symptoms in older-old participants (74.1-85 years). Moreover, older-old participants experienced fewer symptoms of anxiety (ratio = .85, 95% confidence interval [CI], .77-.94), depression (ratio = .90, 95% CI, .82-.98), and total affective symptoms (ratio = .87, 95% CI, .79-.94) if their pain fluctuated more. No such association was evident in younger-old participants (65-74.0 years). These findings imply that stable pain levels are more detrimental to mental health than fluctuating pain levels in older persons.Copyright © 2018 The American Pain Society. Published by Elsevier Inc. All rights reserved.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…