• J. Gastroenterol. Hepatol. · Aug 2016

    Review

    Update on therapeutic interventions for the management of achalasia.

    • Nishmi Gunasingam, Adam Perczuk, Michael Talbot, Arthur Kaffes, and Payal Saxena.
    • Department of Gastroenterology and Hepatology, St Vincent's Hospital, Australia.
    • J. Gastroenterol. Hepatol. 2016 Aug 1; 31 (8): 1422-8.

    AbstractAchalasia is a primary esophageal motility disorder. It is the absence of peristalsis in the esophageal body and inability of the lower esophageal sphincter to relax, which characterizes this rare condition. Its features typically include dysphagia, regurgitation, chest pain, and weight loss. The ultimate goal in treating achalasia is to relieve the patient's symptoms, improve esophageal emptying, and prevent further dilatation of the esophagus. Current treatment modalities targeted at achalasia include pharmacological therapy, endoscopic therapy, and surgery. This review focuses on the current therapeutic options and explores the role of peroral endoscopic myotomy in the management armamentarium. © 2016 Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd.

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