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J. Thromb. Haemost. · May 2018
Comparative StudyAge-adjusted D-dimer cut-off leads to more efficient diagnosis of venous thromboembolism in the emergency department: a comparison of four assays.
- M Farm, A J Siddiqui, L Onelöv, I Järnberg, J Eintrei, F Maskovic, A Kallner, M Holmström, and J P Antovic.
- Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden.
- J. Thromb. Haemost. 2018 May 1; 16 (5): 866-875.
AbstractEssentials Age-adjusted D-dimer cut-offs decrease the false positives in the elderly. Four D-dimer assays were compared in venous thromboembolism outpatients in an emergency ward. Age-adjusted cut-off resulted in improved specificity with maintained sensitivity for all assays. There was a substantial decrease in false positive results, especially in the older population.© 2018 International Society on Thrombosis and Haemostasis.
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