• Luis A Fernandez, Antonio Di Carlo, Jon S Odorico, Glen E Leverson, Brian D Shames, Yolanda T Becker, L Thomas Chin, John D Pirsch, Stuart J Knechtle, David P Foley, Hans W Sollinger, and Anthony M D'Alessandro.
• Division of Transplantation, University of Wisconsin Medical School, Madison, WI 53792-7375, USA.
• Ann. Surg. 2005 Nov 1; 242 (5): 716-23.

ObjectiveThe outcomes of simultaneous pancreas-kidney (SPK) transplantation with donor organs procured from donation after cardiac death (DCD) are compared with transplants performed with donor organs recovered from donation after brain death (DBD).Summary Background DataConcerns exist regarding the utilization of pancreata obtained from DCD donors. While it is known that DCD kidneys will have a higher rate of DGF, long-term functional graft survival data for DCD pancreata have not been reported.MethodsA retrospective review of all DCD SPK transplants performed at a single center was undertaken.ResultsPatient, pancreas, and kidney survival at 5 years were similar between DCD and DBD organs. Pancreas function and outcomes were indistinguishable between the 2 modes of procurement. As expected, the DCD kidneys had an elevated rate of DGF, which had no significant long-term clinical impact.ConclusionSPK transplantation using selected DCD donors is a safe and viable method to expand the organ pool for transplantation.

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