• J E Barrueco-Francioni, G Seller-Pérez, R Lozano-Saéz, M D Arias-Verdú, G Quesada-García, and M E Herrera-Gutiérrez.
• Intensive Care Medicine Unit, Regional University Hospital of Malaga, Spain; Faculty of Medicine, University of Malaga, Spain.
• Med Intensiva. 2020 Apr 1; 44 (3): 150-159.

ObjectiveComparison of different diagnostic criteria for early liver allograft dysfunction (EAD) and their capability to predict mortality.DesignSingle-center, prospective, cohort study.SettingsICU in a Regional Hospital with a liver transplant program since 1997.Patients253 consecutive patients admitted to our ICU immediately after liver transplantation between 2009 and 2015.Variables Of InterestDifferences in the incidence of EAD and its relation with ICU, Hospital and 2-year mortality depending on the definition applied using as comparator the UNOS (United Network for Organ Sharing) primary non-function criterion.ResultsThe incidence of early liver allograft dysfunction according to UNOS was 13.8%, to Makowka 6.3%, to Ardite 10.7%, to Nanashima 20.6%, to Dhillon 30.8% and to MEAF 13.4%. Kappa test did not show a good correlation among these criteria. EAD was related with ICU mortality for all diagnostic criteria except Dhillon but only UNOS, Makowka and MEAF were associated with 2-year mortality. Hospital mortality was poorly predicted by all criteria except for the MEAF score.ConclusionWe found a poor agreement between different criteria analyzed for the diagnosis of EAD. In our population, the MEAF score showed the best relationship with short- and long-term mortality.Copyright © 2018 Elsevier España, S.L.U. y SEMICYUC. All rights reserved.

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