• World Neurosurg · Feb 2019

    Case Reports

    Dural based marginal zone lymphoma in a patient with sarcoidosis: a case report.

    • Kaiyun Yang, Almunder R Algird, and Jian-Qiang Lu.
    • Division of Neurosurgery, Department of Pathology and Molecular Medicine, Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada. Electronic address: Kaiyun.yang@medportal.ca.
    • World Neurosurg. 2019 Feb 1; 122: 569-572.

    BackgroundPrimary dural-based lymphoma is a rare disease entity. It has been hypothesized that patients with sarcoidosis are at increased risk of developing lymphoma, an association known as "sarcoidosis-lymphoma syndrome," although dural disease has not yet been reported in the literature.Case DescriptionHere we report the first case of dural-based lymphoma in a 60-year-old man with a history of sarcoidosis, in keeping with sarcoidosis-lymphoma syndrome. His dural-based tumor was surgically resected. Pathology examination revealed a marginal zone B-cell lymphoma. Subsequent neural and systemic staging confirmed a localized lymphoma. The patient received local radiotherapy to control leptomeningeal disease.ConclusionsGiven the association between sarcoidosis and lymphoma, we suggest lymphoma to be considered as one of the top differentials for a dural-based mass lesion in patients with sarcoidosis.Copyright © 2018 Elsevier Inc. All rights reserved.

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