• Sharon L Cheatham, Ralf J Holzer, Joanne L Chisolm, and John P Cheatham.
• The Heart Center, Nationwide Children's Hospital, Columbus, Ohio.
• Catheter Cardiovasc Interv. 2013 Nov 1; 82 (5): 816-23.

ObjectivesWe report the Melody valve implanted and/or expanded to 24-mm diameter.BackgroundThe Medtronic Melody valve has been implanted up to 22 mm in the pulmonary position for over a decade.MethodsA retrospective chart review was performed on 82 patients who underwent Melody valve implant. Technical implant method, pre- and postimplant echocardiographic findings, and initial follow-up were reviewed.ResultsBetween 04/2008 and 12/2011, 13 Melody valves were successfully implanted in 11 patients, median age 35 years (range 16-61 years), in the pulmonary (bioprosthetic valve, right ventricle to pulmonary artery conduit, native valve) position (n = 9), tricuspid position (bioprosthetic valve n = 3), and aortic position (bioprosthetic valve n = 1). Ten valves were delivered on a 24-mm balloon in balloon catheter and three were implanted using a 22-mm Ensemble balloon delivery system, followed by postdilation using a 24-mm × 2-cm Atlas balloon catheter. Postimplant, the median peak systolic gradient across the pulmonary valve was 7 mm Hg and median gradient across the tricuspid valve was 3 mm Hg. There was no change in gradient across the Melody valve in the aortic position where valve prosthesis-patient mismatch was present. Postimplant intracardiac echocardiography demonstrated none or mild valve regurgitation. No more than mild regurgitation was noted at a median follow-up of 9.5 months.ConclusionsThe Melody valve can be implanted at 24 mm in the stenotic/regurgitant bioprosthetic pulmonary, tricuspid, and aortic valve, dysfunctional right ventricle to pulmonary artery conduit, and the native right ventricular outflow tract, whereas the valve remains competent with only mild regurgitation.Copyright © 2013 Wiley Periodicals, Inc.

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