• Medicina intensiva · May 2018

    Review

    Ethics research in critically ill patients.

    • A Estella.
    • Unidad de Gestión clínica de Medicina Intensiva, Hospital del SAS de Jerez, Jerez, España. Electronic address: litoestella@hotmail.com.
    • Med Intensiva. 2018 May 1; 42 (4): 247-254.

    AbstractResearch in critical care patients is an ethical obligation. The ethical conflicts of intensive care research arise from patient vulnerability, since during ICU admission these individuals sometimes lose all or part of their decision making capacity and autonomy. We therefore must dedicate effort to ensure that neither treatment (sedation or mechanical ventilation) nor the disease itself can affect the right to individual freedom of the participants in research, improving the conditions under which informed consent must be obtained. Fragility, understood as a decrease in the capacity to tolerate adverse effects derived from research must be taken into account in selecting the participants. Research should be relevant, not possible to carry out in non-critical patients, and a priori should offer potential benefits that outweigh the risks that must be known and assumable, based on principles of responsibility.Copyright © 2018 Elsevier España, S.L.U. y SEMICYUC. All rights reserved.

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