• Clinical rheumatology · Jun 1983

    Hypothalamic-pituitary-adrenal (HPA) axis function in patients receiving long-term intra-articular corticosteroids.

    • D M Reid, S Patel, I W Reid, C J Eastmond, and J A Rennie.
    • Clin. Rheumatol. 1983 Jun 1; 2 (2): 159-61.

    AbstractThe hypothalamic-pituitary-adrenal (HPA) axis function of eight patients with rheumatoid arthritis receiving regular intra-articular methyl prednisolone acetate was studied. Tests of the HPA axis 5-7 weeks after the last injection revealed suppression in two patients. Some patients receiving intra-articular corticosteroids may therefore have abnormal responses to stress.

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