• World Neurosurg · Nov 2018

    A Three-Dimensional Finite Element Analysis of Adjacent Segment Disc Degeneration Induced by Transforaminal Lumbar Interbody Fusion Following Pedicle Screw Fixation.

    • Tuan-Mao Guo, Jian Lu, Yan-Li Xing, Guo-Xiong Liu, Hai-Yun Zhu, Lan Yang, and Xi-Min Qiao.
    • Department of Orthopedics, Xianyang Central Hospital, Xianyang, P.R. China.
    • World Neurosurg. 2018 Nov 29.

    BackgroundTransforaminal lumbar interbody fusion (TLIF) is an effective treatment of upper lumbar intervertebral disk herniation. However, its clinical efficacy for adjacent segment disk degeneration (ASDD) remains undefined. Therefore, the biomechanical evaluation of ASDD caused by TLIF after pedicle screw fixation (PSF) was explored via a 3-dimensional (3D) finite element analysis.MethodsComputed tomography images of a healthy male adult volunteer were used in this study. A L3-4 3D finite element model (model) was successfully constructed using Pro/E software, which was also used to establish the L4-5 of the TLIF, PSF, and PSF + TLIF models. Under the same loading conditions, the protrusion and retraction of the adjacent intervertebral disk and the stress distribution of the annulus fibrosis, facet joint, and articular process in the TLIF, PSF, and PSF + TLIF models were all compared.ResultsProtrusion and retraction of the adjacent intervertebral disk were more notable in the PSF + TLIF model than in the PSF model under the same loading conditions. The stress of the annulus fibrosis of the PSF + TLIF model was stronger relative to that of the PSF model under flexion, extension, or lateral bending. The stress of the articular process of the PSF + TLIF model was also stronger than that of the PSF model under extension or lateral bending.ConclusionsThis study provides evidence that TLIF may aggravate ASDD after PSF. Furthermore, the findings provided in this report represent the theoretic basis for the clinical analysis of ASDD caused by TLIF after PSF.Copyright © 2018 Elsevier Inc. All rights reserved.

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