• Susan V Brammer.
• University of Cincinnati, Cincinnati, Ohio. Electronic address: susan.brammer@uc.edu.
• Pain Manag Nurs. 2018 Dec 1; 19 (6): 580-584.

Specific Clinical IssueThe purpose of this clinical consultation is to offer nurses evidence-based strategies to provide holistic care to their patients with comorbid depression and pain. The combination of depression and pain is common and, if not managed effectively, has negative outcomes. Treatment-resistance is one negative outcome. The worst-case scenario for unrelieved depression and/or pain is suicide.Major Practice Recommendations Based On Best EvidenceAntidepressants, particularly duloxetine, have had efficacy for pain and depression. Cognitive behavioral therapy, an evidence-based treatment for depression, has been found to decrease pain. Examples of additional interventions include exercise, relaxation techniques, mindfulness, and music. Providing holistic nursing care and working with other disciplines optimizes more effective management of these co-occurring conditions.Copyright © 2018 American Society for Pain Management Nursing. Published by Elsevier Inc. All rights reserved.

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