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Zhonghua Liu Xing Bing Xue Za Zhi · Nov 2018
Review[Progress in research of influence of gene polymorphisms on immune response].
- J Q Cao, J X Li, Y Y Wang, and F C Zhu.
- School of Public Health, Nanjing Medical University, Nanjing 211166, China.
- Zhonghua Liu Xing Bing Xue Za Zhi. 2018 Nov 10; 39 (11): 1515-1518.
AbstractGenes play an important role in the immune system response, and different gene loci may result in different vaccine immune response rates. This review focuses on the correlation between gene polymorphisms and vaccine immune response in order to investigate the influence of gene polymorphisms on the immune response to vaccines. It discusses the effect of an individual's immune response after vaccination at genetic level and provides a scientific basis for individualized immune development strategies. It reveals that human leukocyte antigen genes, various cytokines and their receptor genes, and Toll-like receptor genes all affect the vaccine immune response.
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