• J Palliat Med · Feb 2019

    Case Reports

    Resurgence of Eating Disorders with Olanzapine.

    • Kelly L Wu, Amanda K Lorenz, Kelly J Christensen, Molly A Feely, Elise C Carey, and Jacob J Strand.
    • 1 Center for Palliative Medicine, Division of General Internal Medicine, Mayo Clinic, Phoenix, Arizona.
    • J Palliat Med. 2019 Feb 1; 22 (2): 231-233.

    BackgroundOlanzapine is commonly utilized in palliative care for the treatment of nausea, and a known side effect of olanzapine is increased appetite. Olanzapine is also known to cause re-emergence of eating disorders (EDs) in patients utilizing olanzapine for its antipsychotic effects. It is unclear to what extent this may also occur in patients with serious/life-limiting illness.Methods And ResultsWe present a case of a 70-year-old female with recurrent ovarian cancer and a history of bulimia nervosa (BN) that developed resurgence of her BN after initiation of olanzapine for cancer-associated nausea. Her BN resolved with reducing the dose of olanzapine.ConclusionIt is important to recognize that recurrence of EDs can occur when using olanzapine in the palliative care setting.

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