• Behav. Brain Res. · Mar 2011

    Adaptation of a novel operant orofacial testing system to characterize both mechanical and thermal pain.

    • Todd A Nolan, Jordan Hester, Yvonne Bokrand-Donatelli, Robert M Caudle, and John K Neubert.
    • Center for Comprehensive Pain Research, University of Florida, Gainesville, FL, USA.
    • Behav. Brain Res. 2011 Mar 1; 217 (2): 477-80.

    AbstractMechanical pain sensitivity is characteristic of many orofacial pain conditions; however, few models exist to quantify this pain. Here we evaluated a novel adaptation of our existing operant system to characterize orofacial pain following mechanical and thermal stimuli. We demonstrate that the operant system is able to detect painful and analgesic responses to mechanical stimuli. These findings allow comparison of both mechanical and thermal stimuli using the same outcome measures.Copyright © 2010 Elsevier B.V. All rights reserved.

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