• J. Cardiothorac. Vasc. Anesth. · Oct 2019

    Review

    Trends and Updates on Cardiopulmonary Bypass Setup in Pediatric Cardiac Surgery.

    • Ravi Medikonda, Chin Siang Ong, Rajeev Wadia, Dheeraj Goswami, Jamie Schwartz, Larry Wolff, Narutoshi Hibino, Luca Vricella, Daniel Nyhan, Viachaslau Barodka, and Jochen Steppan.
    • Johns Hopkins School of Medicine, Baltimore, MD.
    • J. Cardiothorac. Vasc. Anesth. 2019 Oct 1; 33 (10): 2804-2813.

    AbstractPerfusion strategies for cardiopulmonary bypass have direct consequences on pediatric cardiac surgery outcomes. However, inconsistent study results and a lack of uniform evidence-based guidelines for pediatric cardiopulmonary bypass management have led to considerable variability in perfusion practices among, and even within, institutions. Important aspects of cardiopulmonary bypass that can be optimized to improve clinical outcomes of pediatric patients undergoing cardiac surgery include extracorporeal circuit components, priming solutions, and additives. This review summarizes the current literature on circuit components and priming solution composition with an emphasis on crystalloid, colloid, and blood-based primes, as well as mannitol, bicarbonate, and calcium.Copyright © 2019 Elsevier Inc. All rights reserved.

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