• Critical care clinics · Apr 2019

    Review Case Reports

    Angiotensin II in Vasodilatory Shock.

    • Brett J Wakefield, Laurence W Busse, and Ashish K Khanna.
    • Department of General Anesthesiology, Anesthesiology Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA; Department of Anesthesiology, Division of Critical Care Medicine, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8054, St Louis, MO 63110, USA.
    • Crit Care Clin. 2019 Apr 1; 35 (2): 229-245.

    AbstractThe Angiotensin II for the Treatment of Vasodilatory Shock (ATHOS-3) trial demonstrated the vasopressor effects and catecholamine-sparing properties of angiotensin II. As a result, the Food and Drug Administration has approved angiotensin II for the treatment of vasodilatory shock. This review details the goals of treatment of vasodilatory shock in addition to the history, current use, and recent research regarding the use of angiotensin II. An illustrative case of the use of angiotensin II is also incorporated for understanding the clinical utility of the drug.Copyright © 2018 Elsevier Inc. All rights reserved.

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