• Critical care clinics · Apr 2019

    Review

    Osteoporosis and the Critically Ill Patient.

    • Neil R Orford, Julie A Pasco, and Mark A Kotowicz.
    • University Hospital Geelong, Barwon Health, Bellerine St, Geelong, VIC 3220, Australia; Australian and New Zealand Intensive Care Research Centre (ANZIC-RC), Department of Epidemiology and Preventive Medicine (DEPM), Monash University, 553 St Kilda Rd, Melbourne, VIC 3004, Australia; School of Medicine, Deakin University, 75 Pigdons Rd, Geelong, VIC 3216, Australia. Electronic address: neilo@barwonhealth.org.au.
    • Crit Care Clin. 2019 Apr 1; 35 (2): 301-313.

    AbstractImproved survival after critical illness has led to recognition of impaired recovery following critical illness as a major public health problem. A consistent association between critical illness and accelerated bone loss has been described, including changes in bone turnover markers, bone mineral density, and fragility fracture rate. An association between accelerated bone turnover and increased mortality after critical illness is probable. Assessment of the effect of antifracture agents on fracture rate and mortality in the high-risk population of postmenopausal women with prolonged ventilation is warranted.Crown Copyright © 2018. Published by Elsevier Inc. All rights reserved.

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