• Acta Neurochir. Suppl. · Jan 2017

    Awake Craniotomy for Tumor Resection: Further Optimizing Therapy of Brain Tumors.

    • H Maximilian Mehdorn, Felix Schwartz, and Juliane Becker.
    • Department of Neurosurgery, University Hospitals Kiel, Sternwartenweg 1a, Kiel, D - 24105, Germany. mehdorn@nch.uni-kiel.de.
    • Acta Neurochir. Suppl. 2017 Jan 1; 124: 309-313.

    AbstractIn recent years more and more data have emerged linking the most radical resection to prolonged survival in patients harboring brain tumors. Since total tumor resection could increase postoperative morbidity, many methods have been suggested to reduce the risk of postoperative neurological deficits: awake craniotomy with the possibility of continuous patient-surgeon communication is one of the possibilities of finding out how radical a tumor resection can possibly be without causing permanent harm to the patient.In 1994 we started to perform awake craniotomy for glioma resection. In 2005 the use of intraoperative high-field magnetic resonance imaging (MRI) was included in the standard tumor therapy protocol. Here we review our experience in performing awake surgery for gliomas, gained in 219 patients.Patient selection by the operating surgeon and a neuropsychologist is of primary importance: the patient should feel as if they are part of the surgical team fighting against the tumor. The patient will undergo extensive neuropsychological testing, functional MRI, and fiber tractography in order to define the relationship between the tumor and the functionally relevant brain areas. Attention needs to be given at which particular time during surgery the intraoperative MRI is performed. Results from part of our series (without and with ioMRI scan) are presented.

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