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- Frank Weber, Rahul Guha, Guy Weinberg, Frank Steinbach, and Marina Gitman.
- From the Department of Anesthesiology.
- A A Pract. 2019 Jun 15; 12 (11): 438-440.
AbstractLocal anesthetic toxicity is a rare but serious complication of local anesthetic administration. Although lidocaine has a safety profile superior to other amide local anesthetics, we report a case of cardiac arrest after intranasal injection of lidocaine. The case involves a 22-year-old healthy woman who experienced pulseless electrical activity shortly after a submucosal injection of 2.2 mg/kg of lidocaine with epinephrine. Resuscitative efforts were unsuccessful until a bolus of intralipid was given. This case emphasizes that even a "low" dose of a less lipophilic drug has the potential for severe toxicity.
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