• Xiaoke Wang, Yang Chen, Xiujuan Wu, and Hongliang Zhang.
• Department of Neurosurgery, the Second Hospital of Jilin University, Jilin University, Changchun, China.
• World Neurosurg. 2019 May 1; 125: 117-122.

BackgroundInflammatory myofibroblastic tumor (IMT) is an indolent tumor mainly affecting children and young adults. As a rare mesenchymal tumor with unknown etiology and pathogenesis, IMT has a predilection for the lung and abdominopelvic region. Previous literature featuring IMT in the central nervous system (IMT-CNS) is rare. The clinical symptoms and radiologic features of IMT-CNS are not specific; therefore, the diagnosis is predominately based on the histopathologic and immunohistochemical analysis of the specimen.Case DescriptionWe herein present a case of a 21-year-old woman who complained of bilateral blurred vision for 15 days. Head magnetic resonance imaging demonstrated a round-shaped and irregular lesion located in the right frontal lobe. The boundary of the lesion was clear, and the lesion was homogeneously enhanced. Peripheral edema of the lesion was observed, and the mass effect was obvious. Supratentorial craniotomy tumor resection was performed. Histopathologic and immunohistochemical analysis revealed IMT, which had negative expression of anaplastic lymphoma kinase.ConclusionsRemission of her symptoms was observed, and no recurrence was recorded during a 6-month follow-up.Copyright © 2019 Elsevier Inc. All rights reserved.

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