• Int J Obstet Anesth · Aug 2019

    Case Reports

    Maternal respiratory distress and successful reversal with sugammadex during intrauterine transfusion with fetal paralysis.

    • A Munro, D McKeen, and J Coolen.
    • Department of Women's & Obstetric Anaesthesia, IWK Health Centre, Halifax, Nova Scotia, Canada; Department of Anesthesia, Dalhousie University, Halifax, Nova Scotia, Canada. Electronic address: ammunro@dal.ca.
    • Int J Obstet Anesth. 2019 Aug 1; 39: 129-131.

    AbstractA 70 kg, 34-year-old woman at 29 weeks-of-gestation required intrauterine transfusion for Rh (D) alloimmunization. In the ambulatory treatment clinic, 19 mg of rocuronium was administered intramuscularly in split doses into the fetal buttock. The fetus moved and inadvertent maternal neuromuscular blockade occurred, leading to respiratory distress. The patient was transferred to the operating room where she had poor muscle tone, dyspnea and dysphonia. Sugammadex 100 mg was administered intravenously and complete resolution of neuromuscular blockade was demonstrated using a Neuromuscular Transmission™ monitor. When neuromuscular blocking agents are administered in ambulatory settings, management protocols, reversal agents, and skilled assistance should be immediately available for managing potentially life-threatening complications.Copyright © 2019 Elsevier Ltd. All rights reserved.

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