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- Michael W Manning, William Jonathan Dunkman, and Timothy E Miller.
- Division of Cardiothroacic Anesthesia, Department of Anesthesiology, Duke University, Durham, North Carolina.
- J Surg Oncol. 2017 Oct 1; 116 (5): 592-600.
AbstractGoal-directed fluid therapy (GDFT) seeks to improve outcomes through individualized optimization of oxygen delivery using IV fluid and vasoactive infusions. Trials of GDFT show clinical benefits over traditional liberal fluid administration, but fail to demonstrate benefits when compared to a restrictive strategy within an optimized enhanced recovery protocol. The ideal monitors, hemodynamic goals, and fluid administration strategy are not well established but may be less important than rational application of thoughtful fluid management strategies.© 2017 Wiley Periodicals, Inc.
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