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Paediatric anaesthesia · Mar 2019
Multicenter Study Observational StudyStatistical Analysis Plan for "An international multicenter study of isoelectric electroencephalography events in infants and young children during anesthesia for surgery".
- Ian Yuan, Vanessa A Olbrecht, Janell L Mensinger, Bingqing Zhang, Andrew J Davidson, Britta S von Ungern-Sternberg, Justin Skowno, QingQuan Lian, XingRong Song, Pin Zhao, JianMin Zhang, MaZhong Zhang, YunXia Zuo, Jurgen C de Graaff, Laszlo Vutskits, Peter Szmuk, and Charles D Kurth.
- Department of Anesthesiology and Critical Care Medicine, Perelman School of Medicine, The Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania.
- Paediatr Anaesth. 2019 Mar 1; 29 (3): 243-249.
AbstractThis Statistical Analysis Plan details the statistical procedures to be applied for the analysis of data for the multicenter electroencephalography study. It consists of a basic description of the study in broad terms and separate sections that detail the methods of different aspects of the statistical analysis, summarized under the following headings (a) Background; (b) Definitions of protocol violations; (c) Definitions of objectives and other terms; (d) Variables for analyses; (e) Handling of missing data and study bias; (f) Statistical analysis of the primary and secondary study outcomes; (g) Reporting of study results; and (h) References. It serves as a template for researchers interested in writing a Statistical Analysis Plan.© 2019 John Wiley & Sons Ltd.
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