Statistical Analysis Plan for "An international multicenter

Paediatric anaesthesia · Mar 2019

Multicenter Study Observational Study

Statistical Analysis Plan for "An international multicenter study of isoelectric electroencephalography events in infants and young children during anesthesia for surgery".

This Statistical Analysis Plan details the statistical procedures to be applied for the analysis of data for the multicenter electroencephalography study. It consists of a basic description of the study in broad terms and separate sections that detail the methods of different aspects of the statistical analysis, summarized under the following headings (a) Background; (b) Definitions of protocol violations; (c) Definitions of objectives and other terms; (d) Variables for analyses; (e) Handling of missing data and study bias; (f) Statistical analysis of the primary and secondary study outcomes; (g) Reporting of study results; and (h) References. It serves as a template for researchers interested in writing a Statistical Analysis Plan.

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- Ian Yuan, Vanessa A Olbrecht, Janell L Mensinger, Bingqing Zhang, Andrew J Davidson, Britta S von Ungern-Sternberg, Justin Skowno, QingQuan Lian, XingRong Song, Pin Zhao, JianMin Zhang, MaZhong Zhang, YunXia Zuo, Jurgen C de Graaff, Laszlo Vutskits, Peter Szmuk, and Charles D Kurth.
- Department of Anesthesiology and Critical Care Medicine, Perelman School of Medicine, The Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania.
- Paediatr Anaesth. 2019 Mar 1; 29 (3): 243-249.
AbstractThis Statistical Analysis Plan details the statistical procedures to be applied for the analysis of data for the multicenter electroencephalography study. It consists of a basic description of the study in broad terms and separate sections that detail the methods of different aspects of the statistical analysis, summarized under the following headings (a) Background; (b) Definitions of protocol violations; (c) Definitions of objectives and other terms; (d) Variables for analyses; (e) Handling of missing data and study bias; (f) Statistical analysis of the primary and secondary study outcomes; (g) Reporting of study results; and (h) References. It serves as a template for researchers interested in writing a Statistical Analysis Plan.© 2019 John Wiley & Sons Ltd.

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Statistical Analysis Plan for "An international multicenter study of isoelectric electroencephalography events in infants and young children during anesthesia for surgery".

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