• Infect Disord Drug Targets · Apr 2009

    Review

    Drug targets in infections with Ebola and Marburg viruses.

    • Olinger G Gene, Biggins E Julia, Melanson R Vanessa, Wahl-Jensen Victoria, Geisbert W Thomas, and Hensley E Lisa.
    • United States Army Medical Research Institute of Infectious Diseases, Division of Virology, Frederick, Maryland 21702-5011, USA.
    • Infect Disord Drug Targets. 2009 Apr 1; 9 (2): 191-200.

    AbstractThe development of antiviral drugs for Ebola and Marburg viruses has been slow. To date, beyond supportive care, no effective treatments, prophylactic measures, therapies, or vaccines are approved to treat or prevent filovirus infections. In this review, we examine the current treatments available to administer care for filovirus infection, the potential therapeutic targets that can be used for filovirus drug development, and the various drug targeting techniques used against filoviruses.

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