• Anaesth Intensive Care · May 1985

    Hypotensive effect of mannitol administered rapidly.

    • C M Domaingue and D H Nye.
    • Anaesth Intensive Care. 1985 May 1; 13 (2): 134-6.

    AbstractMannitol is an osmotic diuretic commonly used to reduce intracranial pressure. While various side-effects, including hyperosmolar states, precipitate reduction in intracranial pressure, rebound phenomenon and hypervolaemia have been described, hypotension due to rapid administration has not been widely recognised.

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