• Tokunori Kanazawa, Tomoru Miwa, Takenori Akiyama, Kentaro Ohara, Kenzo Kosugi, Masaaki Nishimoto, and Kazunari Yoshida.
• Department of Neurosurgery, Keio University School of Medicine, Tokyo, Japan.
• World Neurosurg. 2019 Jun 1; 126: 120-123.

BackgroundAngiosarcoma often arises as a cutaneous disease in the scalp and the face; however, subdural hematoma (SDH) associated with angiosarcoma is extremely rare.Case DescriptionA 72-year-old woman visited our hospital with gait disorder and progressive consciousness disturbance approximately 3 months after a minor head injury. Initially, on reviewing the results of imaging studies, she was diagnosed with traumatic chronic SDH. Despite repeated operations thereafter, including the embolization of the middle meningeal artery, her general condition progressively worsened, and computed tomography of head repeatedly showed the recurrence of SDH. Based on histopathologic and intraoperative findings, she was finally diagnosed with angiosarcoma originating from the skull. She died shortly thereafter because of aggressive recurrent intracranial SDH caused by leptomeningeal dissemination.ConclusionsIn addition to cancers metastatic to the skull or dura mater, angiosarcoma should be included in the differential diagnosis for patients with repeated SDH and bone defect. An effective treatment for angiosarcoma with SDH that shows an unfavorable prognosis has not been established; however, an early diagnosis might be useful for a novel treatment.Copyright © 2019 Elsevier Inc. All rights reserved.

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