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Comparative Study
Evaluation of an electrochemical sensor for measuring blood ketones.
- H A Byrne, K L Tieszen, S Hollis, T L Dornan, and J P New.
- Department of Diabetes and Endocrinology, Hope Hospital, Salford, U.K.
- Diabetes Care. 2000 Apr 1; 23 (4): 500-3.
ObjectiveTo evaluate the performance of a hand-held ketone sensor that is able to measure blood beta-hydroxybutyrate (beta-HBA) concentrations within 30 s in patients with diabetic ketoacidosis (DKA) and patients who attend a weight management clinic.Research Design And MethodsTwo groups of patients were studied: 19 patients admitted with DKA and 156 patients attending a weight management clinic. Paired capillary and venous whole blood samples were measured using the ketone sensor and also using an enzymatic laboratory reference method.ResultsThe ketone sensor accurately measured beta-HBA concentrations in patients with DKA (limits of agreement -0.9 to + 1.0 mmol/l) or starvation-induced ketonemia (limits of agreement -0.5 to +0.5 mmol/l).ConclusionsThis ketone sensor accurately measures whole blood beta-HBA concentrations within 30 s.
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