• Sonia Santos Lasaosa, Jorge Navarro Calzada, Alba Velázquez Benito, and Cristina Pérez Lázaro.
• Department of Neurology, Clinical University Hospital Lozano Blesa, Zaragoza, Spain. ssantosl@yahoo.com
• Headache. 2011 Oct 1; 51 (9): 1445-9.

BackgroundIt has been proposed that desaturation of oxygen during an apnea event is the trigger for cluster headache. Obstructive sleep apnea has been associated with a higher than normal cardiovascular morbidity and mortality. Some obstructive sleep apnea syndrome patients lack the sleep-related, nocturnal decrease, or "dip" in blood pressure, which is seen in normal individuals.ObjectiveThe aim of this study is to assess whether this non-dipper pattern is present in cluster headache patients.Design And MethodsA total of 30 normotensive cluster headache patients underwent an ambulatory blood pressure monitoring. "Non dippers" were defined as patients with a nighttime mean blood pressure fall <10%.ResultsFifteen cluster headache patients (50%) were non-dippers, a frequency higher than expected. The pattern of nocturnal non-dipping is associated with a higher body mass index. Non-dipper patients displayed higher mean nighttime systolic and diastolic blood pressure. No significant difference was observed in the mean 24-hour and daytime blood pressure.ConclusionsThe high incidence (50%) of non-dipper pattern in both processes, cluster headache and obstructive sleep apnea syndrome, provides support for the hypothesis of a relationship between theses 2 disorders.© 2011 American Headache Society.

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