• Keiji Nagata, Noriko Yoshimura, Hiroshi Hashizume, Hiroshi Yamada, Yuyu Ishimoto, Shigeyuki Muraki, Yukihiro Nakagawa, Akihito Minamide, Hiroyuki Oka, Hiroshi Kawaguchi, Sakae Tanaka, Kozo Nakamura, and Munehito Yoshida.
• Department of Orthopaedic Surgery, Wakayama Medical University, 811-1 Kimidera, Wakayama City, Wakayama, 641-8509, Japan.
• Eur Spine J. 2019 May 1; 28 (5): 1217-1224.

PurposeWe previously revealed a prevalence rate of 24.4% for cervical cord compression (CCC) in a population-based magnetic resonance imaging study. This study aimed to investigate the occurrence of cervical myelopathy (CM) among CCC cases and to reveal the predictors for CM.MethodsThis study is a part of "The Wakayama Spine Study," a large-scale population-based MRI cohort study. At baseline, 238 patients were diagnosed with CCC. We followed 238 patients who had CCC for more than 4 years, of which 158 (mean age, 68.9 years) participated in the second survey (follow-up rate, 66.3%). In the second survey, de novo CM was defined clinically as the presence of myelopathic signs (e.g., Hoffmann reflex, hyperreflexia of the patellar tendon, and Babinski reflex). Physical performance on 10-s grip and release test (GRT), grip strength, 6-m walking time at a usual and a maximal pace, step length at a usual and a maximal pace, chair stand time (CST), and one-leg standing (OLS) time was measured.ResultsAmong the 158 participants, nine (mean age, 68.8 years; incidence rate, 6.3%) were newly diagnosed with CM in the second survey. CST, 6-m walking time at a usual and a maximal pace, and step length at a maximal pace had already decreased in the de novo CM (+) participants at baseline compared to baseline findings of de novo (-) CM participants, but not the grip strength, OLS, or GRT.ConclusionsWe clarified the incidence rate of CM in CCC patients and the predictors of de novo CM. These slides can be retrieved under Electronic Supplementary Material.

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