• World Neurosurg · Jun 2019

    Case Reports

    H3k27m- Positive Primary Spinal Gliobastoma Presenting With Haemorrhage- A Rare Clinical Entity.

    • Alok Uppar, Subhas K Konar, Nandeesh B N, and Dhaval Shukla.
    • Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bangalore, India.
    • World Neurosurg. 2019 Jun 1; 126: 223-227.

    BackgroundPrimary spinal glioblastoma multiforme is a rare and aggressive spinal tumor with dismal outcomes CASE DESCRIPTION: We have presented an unusual case-the first, to the best of our knowledge, to be reported-with intratumoral hemorrhage and sudden-onset quadriplegia in a patients with primary spinal glioblastoma multiforme. The patient underwent emergency surgical decompression. The patient died after a prolonged intensive care unit stay.ConclusionThe tumor was positive for histone molecular alteration, H3K27M.Copyright © 2019 Elsevier Inc. All rights reserved.

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