• Fernando Estévez-López, María Rodriguez-Ayllon, Alberto Soriano-Maldonado, Pedro Acosta-Manzano, Víctor Segura-Jiménez, Inmaculada C Álvarez-Gallardo, Manuel Pulido-Martos, Manuel Herrador-Colmenero, Rinie Geenen, Ana Carbonell-Baeza, and Manuel Delgado-Fernández.
• Department of Physical Education and Sport, Faculty of Sport Sciences, University of Granada, Granada, Spain.
• Pain Med. 2019 Dec 1; 20 (12): 2506-2515.

ObjectiveTo analyze 1) the independent association of physical fitness, positive affect, and negative affect with the different dimensions of fatigue (general fatigue, physical fatigue, reduced activity, reduced motivation, and mental fatigue) and 2) whether the interactions of physical fitness, positive affect, and negative affect were associated with fatigue over and above the independent association.DesignCross-sectional study in 420 women with fibromyalgia.SettingFibromyalgia associations from southern Spain.MethodsPhysical fitness was measured by performance-based tests, and questionnaires were used to measure positive affect, negative affect, and different dimensions of fatigue (general fatigue, physical fatigue, reduced activity, reduced motivation, and mental fatigue). Age, body mass index, and current pain level were included as potential confounders in all analyses.ResultsPhysical fitness was independently associated with general fatigue, physical fatigue, and reduced activity (all P ≤ 0.02). Positive affect was independently associated with all fatigue dimensions (all P < 0.001). Negative affect was independently associated with general fatigue, physical fatigue, reduced motivation, and mental fatigue (all P ≤ 0.04). The interaction of overall physical fitness and positive affect was related to general fatigue and physical fatigue (all P ≤ 0.02). Women with fibromyalgia with higher levels of overall physical fitness and positive affect showed the lowest general fatigue and physical fatigue.ConclusionsIn women with fibromyalgia, positive affect was independently and consistently associated with all dimensions of fatigue. The combination of higher levels of overall physical fitness and positive affect might serve as a buffer against general and physical fatigue in women with fibromyalgia.© 2019 American Academy of Pain Medicine. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

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