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Review
A review on the management of cerebral vasospasm following aneurysmal subarachnoid haemorrhage.
- Kenny Li, Christen D Barras, Ronil V Chandra, Hong K Kok, Julian T Maingard, Nicole S Carter, Jeremy H Russell, Leon Lai, Mark Brooks, and Hamed Asadi.
- School of Medicine, Faculty of Health, Deakin University, Geelong, Victoria, Australia. Electronic address: kenny.li@live.com.au.
- World Neurosurg. 2019 Jun 1; 126: 513-527.
BackgroundDespite decades of research, cerebral vasospasm (CV) continues to account for high morbidity and mortality in patients who survive their initial aneurysmal subarachnoid hemorrhage.ObjectiveTo define the scope of the problem and review key treatment strategies that have shaped the way CV is managed in the contemporary era.MethodsA literature search was performed of CV management after aneurysmal subarachnoid hemorrhage.ResultsRecent advances in neuroimaging have led to improved detection of vasospasm, but established treatment guidelines including hemodynamic augmentation and interventional procedures remain highly variable among neurosurgical centers. Experimental research in subarachnoid hemorrhage continues to identify novel targets for therapy.ConclusionsProactive and preventive strategies such as oral nimodipine and endovascular rescue therapies can reduce the morbidity and mortality associated with CV.Copyright © 2019 Elsevier Inc. All rights reserved.
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