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Neuroimaging Clin. N. Am. · May 2019
ReviewThe Connection Between Patent Foramen Ovale and Migraine.
- Preetham Kumar, Yasufumi Kijima, Brian H West, and Jonathan M Tobis.
- Cardiology, University of California, Los Angeles, Room B-976 Factor Building, Box # 951717, Los Angeles, CA 90095-1717, USA.
- Neuroimaging Clin. N. Am. 2019 May 1; 29 (2): 261-270.
Abstract"Observational studies have identified a relationship between patent foramen ovale (PFO) and migraine headache. In people who have migraine with aura, 40% to 60% have a PFO, compared with 20% to 30% in the general adult population. It is hypothesized that migraine, especially migraine with aura, may be triggered by hypoxemia or vasoactive chemicals (eg, serotonin), which are ordinarily metabolized during passage through the lungs. Although PFO closure is currently not a FDA-approved therapy for migraines, randomized trials suggest that this intervention may benefit a subgroup of migraineurs."Copyright © 2019 Elsevier Inc. All rights reserved.
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